A New Option for Knee Pain: Genicular Artery Embolization (GAE)

September 15, 2025 Katie Robbins

Living with knee pain from osteoarthritis? You’re not alone; millions of adults in the U.S. face this challenge daily. While treatments like exercise, medications, and injections help some, others aren’t ready for, or aren’t good candidates for, knee replacement surgery. That’s where Genicular Artery Embolization (GAE) comes in.

What Is GAE?

GAE is a minimally invasive procedure that targets inflammation in the knee joint. Osteoarthritis causes abnormal blood vessels to form in the joint lining, which leads to pain. During GAE, a tiny catheter is guided into the arteries around the knee, and microscopic particles are used to reduce blood flow to these inflamed areas, relieving pain without harming healthy tissue.

What to Expect on Procedure Day

• Performed at an outpatient center
• Light sedation, no general anesthesia
• Small incision in the groin area
• Procedure takes about an hour
• Most patients go home within a couple of hours
• Recovery is quick, light activity within days, back to normal in about a week

Who Can Benefit?

GAE is ideal for adults with mild to moderate knee osteoarthritis who haven’t found relief from conservative treatments and want to avoid surgery. A thorough evaluation ensures the pain is truly from OA and not another condition.

Is It Safe?

Yes. GAE is well-tolerated with minimal side effects like temporary skin warmth or mild bruising. Serious complications are rare when performed by experienced interventional radiologists.

How Does GAE Compare to Other Treatments?

• Exercise, weight loss, and medications remain essential
• Injections offer short-term relief
• Nerve ablation helps some but doesn’t treat inflammation
• Radiation therapy has a limited long-term benefit
• Knee replacement is effective but involves major surgery

GAE offers a middle ground; it’s joint-sparing, minimally invasive, and can provide relief for years.

Insurance Coverage

Coverage varies and is evolving. Our team helps patients navigate insurance approvals and cost estimates so there are no surprises.

Choosing the Right Provider

Look for a team of experienced interventional radiologists. GAE requires specialized skills in imaging and small-vessel techniques. These experts are trained to perform embolization safely and effectively.